Giant Pepperoni-Stuffed Garlic Knot Pizza
Step-by-step instructions
- Preheat your oven to 400°F.
- On a floured surface, roll out the pizza dough into a large rectangle.
- Spread marinara sauce over the dough, leaving a border around the edges.
- Evenly sprinkle shredded mozzarella cheese over the sauce.
- Layer sliced pepperoni on top of the cheese.
- Carefully roll up the dough tightly to form a log.
- Slice the log into 1-inch pieces to create the garlic knots.
- Arrange the garlic knots in a greased cast-iron skillet or baking dish.
- In a small saucepan, melt butter and add minced garlic along with oregano and red pepper flakes.
- Brush this garlic butter mixture generously over the garlic knots.
- Top with grated Parmesan cheese for an extra layer of flavor.
- Bake in the preheated oven for 25-30 minutes until golden brown and fully cooked.
- Serve hot and revel in the deliciousness of your Giant Pepperoni-Stuffed Garlic Knot Pizza!
Best ways to enjoy it
Serve your Giant Pepperoni-Stuffed Garlic Knot Pizza with a side of marinara sauce for dipping. A fresh salad can add a refreshing contrast, making it a complete meal. For those who enjoy a little heat, a sprinkle of extra red pepper flakes can elevate the flavors even more. Pair it with your favorite beverage, whether it’s soda, beer, or a nice glass of red wine for a cozy night in.
Storage and reheating tips
Leftovers? No problem! To store your Giant Pepperoni-Stuffed Garlic Knot Pizza, simply place it in an airtight container in the refrigerator. It will stay fresh for about 3-4 days. When you’re ready to enjoy it again, reheat in the oven at 350°F until warmed through. For longer storage, you can freeze the knots individually, then transfer them to a freezer bag. They’ll keep well for about 2-3 months.
Helpful cooking tips
- Make the dough ahead of time to save on prep work, or opt for store-bought dough for convenience.
- Be generous with the garlic butter mixture for extra flavor!
- Let the garlic knots cool for a few minutes after baking; this will help them hold their shape when serving.
Creative twists
Feel free to switch up the toppings! Use diced bell peppers, black olives, or even crispy bacon for a fun twist. For a vegetarian version, replace the pepperoni with assorted roasted vegetables or a mix of cheeses. And if you love spice, consider adding jalapeños or a spicy Italian sausage!
FAQs
What is the prep time for this recipe?
This Giant Pepperoni-Stuffed Garlic Knot Pizza takes about 15-20 minutes to prepare, plus an additional 25-30 minutes for baking.
Can I make this recipe ahead of time?
Absolutely! You can prepare the garlic knots and assemble them a few hours in advance. Just cover and refrigerate until you’re ready to bake.
Are there any substitutes for pizza dough?
Yes, you can use store-bought dough, gluten-free dough, or even crescent roll dough for a unique take. Just adjust the baking time as needed.
With its delicious layers and easy preparation, this recipe is sure to become a staple in your household. Enjoy every cheesy, garlic-filled bite!

Giant Pepperoni-Stuffed Garlic Knot Pizza
Ingredients
Method
- Preheat your oven to 400°F.
- On a floured surface, roll out the pizza dough into a large rectangle.
- Spread marinara sauce over the dough, leaving a border around the edges.
- Evenly sprinkle shredded mozzarella cheese over the sauce.
- Layer sliced pepperoni on top of the cheese.
- Carefully roll up the dough tightly to form a log.
- Slice the log into 1-inch pieces to create the garlic knots.
- Arrange the garlic knots in a greased cast-iron skillet or baking dish.
- In a small saucepan, melt butter and add minced garlic along with oregano and red pepper flakes.
- Brush this garlic butter mixture generously over the garlic knots.
- Top with grated Parmesan cheese for an extra layer of flavor.
- Bake in the preheated oven for 25-30 minutes until golden brown and fully cooked.
- Serve hot and enjoy!







