Crock Pot Mississippi Meatloaf is a comforting dish that every home cook should try at least once. Itโs simple to prepare and allows you to set it and forget it while the flavors meld beautifully in the slow cooker. This delicious meatloaf is customizable to suit your family’s taste, making it an ideal option for busy days when you need a hearty meal without all the fuss.
Recipe Information
Prep Time: 15 minutes
Cook Time: 360 minutes
Total Time: 375 minutes
Servings: 6
Difficulty Level: Easy
Nutrition Information (per serving)
Calories: 320
Protein: 20 grams
Carbohydrates: 14 grams
Fat: 18 grams
Fiber: 0 grams
Sugar: 2 grams
Sodium: 970 mg
Why Make Crock Pot Mississippi Meatloaf
Crock Pot Mississippi Meatloaf is not only easy to prepare but also creates a rich, savory flavor profile that your entire family will love. The combination of au jus gravy mix and ranch seasoning elevates the meatloaf, giving it a mouthwatering taste thatโs truly unique. This recipe is also healthy, packed with protein, and can be served with a variety of sides, making it a versatile addition to your dinner rotation.
How to Make Crock Pot Mississippi Meatloaf Step by Step
Ingredients
1 cup milk (2% or higher)
2 large eggs, well beaten
2 teaspoons granulated sugar
2 (1 ounce) packets au jus gravy mix, divided use
2 (1 ounce) packets ranch seasoning mix, divided use
Directions
- In a bowl, combine milk, eggs, and sugar. Mix well.
- Add the au jus gravy mix and ranch seasoning to the bowl and stir until fully incorporated.
- Shape the meat mixture into a loaf and place it in the crock pot.
- Pour any remaining mixture over the meatloaf.
- Cook on low for 6-8 hours or until the meatloaf reaches the desired doneness.

How to Serve Crock Pot Mississippi Meatloaf
Crock Pot Mississippi Meatloaf pairs wonderfully with creamy mashed potatoes or roasted vegetables. You can also serve it alongside a fresh garden salad for a lighter meal. Drizzled with extra au jus or a tangy barbecue sauce, this meatloaf becomes even more delicious.
How to Store Crock Pot Mississippi Meatloaf
To store leftover Crock Pot Mississippi Meatloaf, place it in an airtight container in the refrigerator for up to four days. When reheating, add a splash of beef broth for moisture and heat in the microwave or oven until warmed through. If you want to freeze the meatloaf, wrap it tightly in plastic wrap and then in aluminum foil. It can be frozen for up to three months; simply thaw in the refrigerator before reheating.
Expert Tips for Cooking Crock Pot Mississippi Meatloaf
- Add chopped vegetables like onions or bell peppers for extra flavor and nutrition.
- For a spicier kick, incorporate some crushed red pepper flakes into the mixture.
- Ensure not to overmix the meat mixture to keep the meatloaf tender.
- Use lean ground beef for a healthier version or substitute with turkey for a lighter option.
- If you prefer a crusty exterior, finish the meatloaf in the oven for a few minutes after cooking in the crock pot.
Delicious Variations of Crock Pot Mississippi Meatloaf
For a spicy twist, try adding jalapeรฑos or hot sauce to the mix. If you want a more herbed flavor, incorporate fresh or dried herbs such as thyme or rosemary. For a citrusy zing, mix in some grated lemon zest. Vegetarians can substitute the ground meat with lentils or a plant-based meat alternative, making this dish suitable for everyone.
Conclusion
Crock Pot Mississippi Meatloaf is a must-try recipe that combines rich flavors and ease of preparation. The slow cooking process allows the ingredients to meld perfectly, creating a dish thatโs not only tasty but also incredibly versatile for any dinner table. Give it a try, and you’ll soon make it a family favorite!

Crock Pot Mississippi Meatloaf
Ingredients
Meatloaf Base
- 1 cup milk (2% or higher)
- 2 large eggs, well beaten
- 2 teaspoons granulated sugar
- 2 packets au jus gravy mix (1 ounce each), divided use
- 2 packets ranch seasoning mix (1 ounce each), divided use
Instructions
Preparation
- In a bowl, combine milk, eggs, and sugar. Mix well.
- Add the au jus gravy mix and ranch seasoning to the bowl and stir until fully incorporated.
- Shape the meat mixture into a loaf and place it in the crock pot.
- Pour any remaining mixture over the meatloaf.
- Cook on low for 6-8 hours or until the meatloaf reaches the desired doneness.
